C# pictureBoxを使わずにOnPaintで描画した画像にMouseUｐなどを使いたい

		private void Form1_Load(object sender, System.EventArgs e)
		{
			this.MouseUp += new System.Windows.Forms.MouseEventHandler(this.Form1_MouseUp);
			
		}
		Point MouseUpLocation = new Point();
		private void Form1_MouseUp(object sender, System.Windows.Forms.MouseEventArgs e)
		{
			Form1 form1 = new Form1();
			MouseUpLocation.X = e.X;
			MouseUpLocation.Y = e.Y;

			
			form1.Focus();
			form1.Invalidate();
		}
		private void Form1_Paint(object sender, System.Windows.Forms.PaintEventArgs e)
		{
			Graphics g = e.Graphics;
			Image image = Image.FromFile(@"C:\1.bmp");
			if(image!=null) g.DrawImage(image,0,1);
			Region region1 = new Region(new Rectangle(0,1,20,30));
			while(true)
			{
				if(region1.IsVisible(MouseUpLocation, e.Graphics))
				{
					if(image!=null) g.DrawImage(image,50,0);
					
					break;
				}
				Application.DoEvents();
			}
			
			if(image!=null) g.DrawImage(image,0,50);
		}